HOME THERAPY AREAS Robust evidence on cardiovascular safety of testosterone replacement therapy 6 February 2025 Testosterone deficiency Testosterone deficiency The TRAVERSE study serves as a pivotal step in providing comprehensive safety data on TRT, especially on testosterone gel, the application form used in this study.1,2In this study summary you will find out more about the cardiovascular TRAVERSE substudy and how it changed the perception of the safety profile of TRT.1,2 References:Bhasin S, et al. Effects of long-term testosterone treatment on cardiovascular outcomes in men with hypogonadism: Rationale and design of the TRAVERSE study. Am Heart J. 2022 Mar;245:41-50.Lincoff AM, et al. Cardiovascular Safety of Testosterone-Replacement Therapy. N Engl J Med. 2023 Jul 13;389(2):107-117. View PDF