HOME THERAPY AREAS FSGS Mechanism of Disease 11 October 2022 Nephrology and Rare Diseases Glomerular Disease Watch how Endothelin-1 and Angiotensin II act in tandem to cause increased proteinuria, podocyte injury and loss, and progressive decline in kidney function in FSGS. THERE IS MORE HERE Specialist information is located in this area. In order to be able to see this, you must verify yourself as a healthcare professional. ?